Ipswich bounced back to winning ways following their first league defeat in 12 games with a thumping 3-1 victory over struggling Millwall.
Delano Burgzorg's winner helped Huddersfield beat Sunderland 2-1 to end a five-game winless run and move six points above the Championship relegation zone.
Kyle Walker-Peters' stunning strike sent promotion-chasing Southampton to a 1-0 victory over Bristol City and extended their unbeaten Championship run to 10 matches.
Struggling Sheffield Wednesday snatched a stoppage-time equaliser against Championship leaders Leicester in a 1-1 draw at Hillsborough.
Leeds maintained their pursuit of the Sky Bet Championship's top two with a 3-1 win against Swansea at Elland Road.
Sammie Szmodics celebrated his new contract by firing a second-half brace to help Blackburn to an enthralling 4-2 victory over Birmingham.
Jeremy Sarmiento produced a moment of magic to give West Brom a precious 1-0 win at Cardiff.
Haji Wright's fifth goal of the season secured Coventry a second consecutive Championship win as they saw off Plymouth 1-0 at the CBS Arena.
Yaser Asprilla's goal saw Watford come back from 2-0 down to beat Norwich 3-2 in an entertaining contest at Vicarage Road.
Two late goals gave QPR a 4-2 victory over 10-man Stoke - their first win in 13 matches and only their second at home since October last year.
Isaiah Jones ended a run of seven matches without a goal by scoring twice to help Middlesbrough to a 4-0 win over Preston at the Riverside.
Rotherham's miserable away form plumbed new depths at Hull, who moved back into the Sky Bet Championship play-offs with a 4-1 win at the MKM Stadium.
West Brom reaffirmed themselves as Championship promotion contenders by way of a comfortable 2-0 win over second-placed Ipswich.
Wayne Rooney collected his first win as Birmingham manager after a 2-1 comeback win against the Sky Bet Championship's bottom club Sheffield Wednesday at St Andrew's.
Mark Sykes blasted a 67th-minute winner as Liam Manning's first home game as Bristol City head coach ended with a 3-2 Championship victory over Middlesbrough.
Blackburn secured a fourth successive away league victory with a 3-0 drubbing of Stoke.
Karlan Grant and Ike Ugbo both scored in stoppage time as Cardiff snatched a dramatic 2-1 victory at 10-man Preston.
Plymouth got back to winning ways with a surprise 2-0 home Championship victory over high-flying Sunderland.
Norwich put their home woes behind them with a hard-fought 1-0 win over QPR in a scrappy Championship encounter.
Matt Godden's goal set Coventry on their way to a 3-0 triumph at The Den, as Joe Edwards suffered his first defeat as Millwall manager.